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NACI mandates Gardasil shot

by Jyoti Pal - January 31, 2007 - 2 comments

Giving a nationwide call, Canada’s National Advisory Committee on Immunization (NACI) on Tuesday released a recommendation urging all females between 9 and 26 to be routinely vaccinated against the human papillomavirus (HPV), a sexually transmitted disease that can cause genital warts and cervical cancer.

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[quote=Jyoti Pal]<div class="flexinode-body flexinode-1"><div class="flexinode-textarea-1"><div class="form-item">
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 <p>Giving a nationwide call, Canada’s National Advisory Committee on Immunization (NACI) on Tuesday released a recommendation urging all females between 9 and 26 to be routinely vaccinated against the human papillomavirus (HPV), a sexually transmitted disease that can cause genital warts and cervical cancer.</p>
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 <img alt="NACI mandates Gardasil shot" src="http://www.themoneytimes.com/filess/vaccine girl_sm.jpg" /><br /><a href="http://www.themoneytimes.com/filess/vaccine girl.jpg">Get original file (7KB)</a>
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 <p>Canada’s expert advisory panel on immunization said that they would like to see all Canadian girls aged 9 to 13 who have not yet become sexually active be immunized with Gardasil, vaccine developed by Merck and Co. to protect against the HPV infection.</p>
<p>The committee also emphasized that females aged 14 to 26 should also be vaccinated, even if they are already sexually active or have had previous pap smear abnormalities or a previous HPV infection.</p>
<p>However, girls under nine, pregnant women and males are not recommended a shot of the vaccine, the panel said.</p>
<p>HPV is a DNA-based virus that infects the skin and mucous membranes of humans.</p>
<p>Gardasil provides protection against about a group of 30 HPVs that are typically transmitted through sexual contact. An estimated 75 per cent of women will have at least one HPV infection in their lifetime, authority states.</p>
<p>While some types of HPV can cause genital warts, others types may lead to cancer.</p>
<p>Developed and marketed by Merck, Gardasil got its FDA approval in June 2006. The vaccine shows protection against infection with HPV types 16 and 18, which together cause 70 percent of cervical cancers. Moreover, it also provides protection from HPV types 6 and 11, which cause 90 percent of genital warts.</p>
<p>In its trails, the vaccine showed 100 percent efficacy against persistent infections, not just incident infections.</p>
<p>Meanwhile as the vaccine does not protect against some specific strains that cause 30 per cent of the malignancies, the panel advises women to continue regular screening for cervical cancer even after vaccination.</p>
<p>The vaccine is expected to cost about $135 per dose, with three doses over six months needed to confer full immunity.</p>
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