Fetal and early childhood exposures to industrial chemicals in the environment can damage the developing brain and can lead to neurodevelopmental disorders (NDDs), a new study revealed.
In their explosive report, researchers from the Harvard School of Public Health and the Mount Sinai School of Medicine talked about a "silent pandemic" of neurodevelopmental disorders caused by toxic chemicals spilling into the environment. They called the pandemic silent because the sub-clinical effects of individual toxic chemicals are not evident in available health statistics.
The two researchers, who have spent decades studying the effects of lead and mercury exposure on the fetus and children, linked industrial chemical to the conditions like autism (a developmental disorder), attention deficit disorder (ADHD), mental retardation and cerebral palsy (a collection of movement disorders caused by brain damage that occurs before, during, or shortly after birth).
In order to identify the industrial chemicals with the potential to damage the developing brain, the scientists systematically examined the publicly available data on chemical toxicity.
They mainly emphasized on only five substances, lead, methylmercury, arsenic, polychlorinated biphenyls (PCBs) and toluene, which had sufficient documentation of toxicity to the developing human brain and found the similar pattern of dangers in each case.
After observing the data, they discovered that 202 industrial chemicals have the significant potentiality to damage the developing human brain. Their list of harmful compounds includes everything from arsenic to benzene and phenol. Nearly half of the agents are universal in industrial processes and products, and could make their way into the environment through air, water and food.
"The human brain is a precious and vulnerable organ. And because optimal brain function depends on the integrity of the organ, even limited damage may have serious consequences," said Philippe Grandjean, adjunct professor at Harvard School of Public Health and the lead author of the study.
In their report, Grandjean and co-author Philip J. Landrigan, Professor at Mount Sinai School of Medicine concluded that millions of children may have suffered brain damage as a result of industrial pollution.
The researchers requested the governments to tighten worldwide controls, and enforce highly efficient public health standards, such as toxicity test of chemicals.
"Even if substantial documentation on their (the tested agents) toxicity is available, most chemicals are not regulated to protect the developing brain," Grandjean said. "Only a few substances, such as lead and mercury, are controlled with the purpose of protecting children. The 200 other chemicals that are known to be toxic to the human brain are not regulated to prevent adverse effects on the fetus or a small child."
In the European Union, 100,000 chemicals were registered for commercial use in 1981, while in the US, 80,000 are registered.