Peterson scored on runs of 5 and 7 yards, and Brett Favre completed 18-of-24 passes for 232 yards, including a 13-yard touchdown toss to tight end Visanthe Shiancoe.
The Vikings (5-0) also scored on a 52-yard fumble return by defensive end Jared Allen, a 1-yard run by Chester Taylor and a 47-yard Ryan Longwell field goal.
Marc Bulger, who replaced Kyle Boller in the fourth quarter, threw a 27-yard scoring pass to Donnie Avery and Josh Brown had a 29-yard field goal for the Rams (0-5).
St. Louis has lost 15 straight games going back to last season. The NFL record for consecutive losses is 26, set by Tampa Bay from 1976 to 1977.
Copyright 2009 by United Press International.
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