It was the first time this season the Reds won a game in their final at-bat.
Gonzalez's third hit and third RBI broke a 3-3 tie with one out in the bottom of the 11th inning in the final contest of the three-game interleague series at Cincinnati's Great American Ball Park.
The shortstop went 7-for-12 in the series.
Jerry Hairston Jr. had one RBI and Ramon Hernandez added a run and three hits for the Reds, whose record rose to 17-3.
The winner was reliever Carlos Fisher (1-0) in his first major league contest.
Cleveland's Luis Valbuena and Grady Sizemore both had one run, two hits and one RBI.
A run scored on a seventh-inning error by Adam Rosales, while Shin-Soo Choo added two hits for the Indians, who went 4-6 on their 10-game road trip.
The losing pitcher was Luis Vizcaino (1-2).
Copyright 2009 by United Press International.
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