Imperial College

Master disease gene is identified

London -- British scientists say they've identified the master gene that causes blood stem cells to turn into disease-fighting immune cells.

Imperial College London researchers say their finding could help scientists boost the body's production of tumor-killing cells, creating new ways to treat cancer.

The researchers said they 'knocked out' the gene in question, known as E4bp4, in a mouse model, thereby creating the world's first animal model entirely lacking so-called natural killer cells, but with all other blood cells and immune cells intact.

Knocking out genes is a technique in which an organism is engineered to carry genes that have been made inoperative or "knocked out" of the organism, Wikipedia said.

Rheumatoid arthritis signal molecule found

London -- British scientists say they have identified a signal molecule made by the body that triggers chronic inflammation in rheumatoid arthritis.

Researchers from Imperial College London say if scientists could block that signal, it might be possible to develop more effective arthritis treatments.

Rheumatoid arthritis signal molecule found

London -- British scientists say they have identified a signal molecule made by the body that triggers chronic inflammation in rheumatoid arthritis.

Researchers from Imperial College London say if scientists could block that signal, it might be possible to develop more effective arthritis treatments.