normalization

Geneticists streamline gene searches

West Lafayette, Ind. -- U.S. geneticists say they've determined a process called "normalization" is no longer necessary during gene searches, thereby saving time and money.

The Purdue University scientists, led by Professor Andrew DeWoody and researcher Matthew Hale, said they have evidence that the step called normalization is no longer necessary due to recent advances in DNA sequencing technology.

When searching for specific genes in a tissue sample, there may be thousands of genes that perform simple housekeeping functions, whereas others expressed in smaller numbers are charged with more complex and important functions. The difficulty is sorting through thousands of genes to find the ones that have unique functions.