Orlando, Fla. -- LeBron James and Mo Williams combined for 64 points Wednesday and Cleveland built a 20-point lead in the fourth quarter before downing Orlando 102-93.
James scored 36 points and got a huge assist from Williams, who made his first nine shots from the field.
Williams scored 22 in the first half and finished with 28 to go with six assists. Shaquille O'Neal contributed 10 points in 20 minutes.
These teams battled in last season's Eastern Conference finals, with Orlando ousting the top-seeded Cavaliers in six games.
Cleveland opened this season with back-to-back losses but has bounced back to win five of its last six.
Orlando, which had won three of its previous four, got 29 points from Vince Carter and 19 from Jameer Nelson.