Houston -- Roy Oswalt defeated Cincinnati for the 22nd time in his career Wednesday, carrying Houston to a 4-1 decision over the Reds.
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Oswalt (12-9) allowed a run on five hits over seven innings. His career record against Cincinnati is a stunning 22-1.
Houston's runs came on two-run shots by Hunter Pence and Ty Wiggington.
Cincinnati has lost three out of four.
The loss went to Josh Fogg (2-7), who surrendered just two runs on six hits in six innings.
Pence's 19th homer of the season gave Houston a 2-1 lead in the fourth.
Wiggington's shot came in the seventh.
LaTroy Hawkins worked the eighth for the Astros and Jose Valverde struck out the side in the ninth for his 34th save.
Houston has won 13 of its last 15 meetings with Cincinnati.
Copyright 2008 by United Press International.
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