Deng also sank nine-of-11 free throws in the Bulls' victory, their second straight after opening the season with a loss.
Derrick Rose contributed 16 points and 13 assists and Joakim Noah posted his third straight double-double with 10 points and 10 rebounds for Chicago.
Portland was led by LaMarcus Aldridge with 33 points and nine rebounds while Brandon Roy contributed 17 points and Marcus Camby pulled down a game-high 11 rebounds.
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