The New York Post said the former Republican Alaskan governor is expected to appear on the Nov. 16 edition of the program to promote her new book, "Going Rogue: An American Life."
Winfrey said last year she wouldn't interview Palin on her chat show until after the election because she didn't want to discuss politics on the program after publicly endorsing Barack Obama.
Obama hadn't appeared on the show since 2007.
Copyright 2009 by United Press International.
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