The Mariners took a 7-1 lead through four frames and easily held on while producing six extra-base hits.
Luke French (3-3) got the win in his fourth start since joining the Mariners in a trade July 31. He made it through six innings, giving up three runs on eight hits while striking out six.
Bill Hall helped stake Seattle to a 3-1 lead with an RBI single in the second and a sacrifice fly in the third, after which the Mariners broke the game open in the fourth.
Wilson hit a one-out, solo homer off David Huff (7-7) and Ichiro Suzuki followed with a double to left. Franklin Gutierrez singled in Suzuki and scored in front of the 17th homer of the season for Lopez.
Copyright 2009 by United Press International.