The Cubs lost their second straight and fell out of a first-place tie with St. Louis in the National League Central.
Jimenez (9-9) brought an 0-3 lifetime record against the Cubs into the game, but Chicago could score only on a double-play grounder in the first and a soft single to shallow center in the sixth by Alfonso Soriano.
Colorado overcame an early 1-0 deficit by scoring three times in the bottom of the first -- two of the runs coming in on a single by Brad Hawpe.
Chris Iannetta added a two-run homer in the fourth, helping the Rockies end a two-game skid.
Sean Marshall (3-7) lasted only two innings, giving up three runs on five hits to take the loss.
Copyright 2009 by United Press International.